Target genes of Topoisomerase IIβ regulate neuronal survival and are defined by their chromatin state
Published inProceedings of the National Academy of Sciences of the United States of America, vol. 109, no. 16, p. E934-943
Publication date2012
Abstract
Keywords
- Animals
- Blotting, Western
- Cell Differentiation/genetics
- Cell Survival/genetics
- Cells, Cultured
- Chromatin/genetics
- DNA Topoisomerases, Type II/genetics/metabolism
- DNA-Binding Proteins/antagonists & inhibitors/genetics/metabolism
- Embryonic Stem Cells/cytology/drug effects/metabolism
- Female
- Gene Expression Profiling
- Gene Expression Regulation, Developmental
- Immunoprecipitation
- Male
- Mice
- Mice, 129 Strain
- Mice, Knockout
- Neurons/cytology/drug effects/metabolism
- Oligonucleotide Array Sequence Analysis
- Piperazines/pharmacology
- Protein Binding
- RNA Interference
- Receptor, Nerve Growth Factor/genetics/metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- Time Factors
- Topoisomerase II Inhibitors/pharmacology
Affiliation entities
Research groups
Citation (ISO format)
TIWARI, Vijay K et al. Target genes of Topoisomerase IIβ regulate neuronal survival and are defined by their chromatin state. In: Proceedings of the National Academy of Sciences of the United States of America, 2012, vol. 109, n° 16, p. E934–943. doi: 10.1073/pnas.1119798109
Main files (1)
Article (Published version)
Identifiers
- PID : unige:43451
- DOI : 10.1073/pnas.1119798109
- PMID : 22474351
Journal ISSN0027-8424