An experimental model to investigate the targeting accuracy of MR-guided focused ultrasound ablation in liver

Petrusca, Lorena; Viallon, Magalie; Breguet, Romain; Terraz, Sylvain; Manasseh, Gibran; Auboiroux, Vincent; Goget, Thomas; Baboi, Loredana Maria; Gross, Patrick; Sekins, K Michael; Becker, Christoph; Salomir, Rares Vincent

doi:10.1186/1479-5876-12-12

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Title		An experimental model to investigate the targeting accuracy of MR-guided focused ultrasound ablation in liver
Authors		Petrusca, Lorena Viallon, Magalie Breguet, Romain Terraz, Sylvain Manasseh, Gibran Auboiroux, Vincent Goget, Thomas Baboi, Loredana Maria Gross, Patrick Sekins, K Michael Becker, Christoph Salomir, Rares Vincent show all authors [1 - 12]
Published in		Journal of Translational Medicine. 2014, vol. 12, 12
Abstract		Magnetic Resonance-guided High Intensity Focused Ultrasound (MRgHIFU) is a hybrid technology that aims to offer non-invasive thermal ablation of targeted tumors or other pathological tissues. Acoustic aberrations and non-linear wave propagating effects may shift the focal point significantly away from the prescribed (or, theoretical) position. It is therefore mandatory to evaluate the spatial accuracy of ablation for a given HIFU protocol and/or device. We describe here a method for producing a user-defined ballistic target as an absolute reference marker for MRgHIFU ablations.
Keywords		Animals — Female — High-Intensity Focused Ultrasound Ablation/methods — Liver/surgery/ultrasonography — Magnetic Resonance Spectroscopy — Models, Animal — Rabbits — Radio Waves — Sonication — Sus scrofa
Identifiers		DOI: 10.1186/1479-5876-12-12 PMID: 24433332
Full text		Article (Published version) (3.4 MB) - Free access Other version: http://www.translational-medicine.com/content/12/1/12/
Structures		Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale
Research groups		Imagerie et radiologie interventionnelle du foie, des voies biliaires et du pancréas (316) Imagerie per-opératoire multi-modalité en radiologie interventionnelle (949)
Citation (ISO format)		PETRUSCA, Lorena et al. An experimental model to investigate the targeting accuracy of MR-guided focused ultrasound ablation in liver. In: Journal of Translational Medicine, 2014, vol. 12, p. 12. doi: 10.1186/1479-5876-12-12 https://archive-ouverte.unige.ch/unige:43199