Clinical response and risk for reported suicidal ideation and suicide attempts in pediatric antidepressant treatment: a meta-analysis of randomized controlled trials

Bridge, Jeffrey; Iyengar, Satish; Salary, Cheryl B; Barbe, Remy; Birmaher, Boris; Pincus, Harold Alan; Ren, Lulu; Brent, David A

doi:10.1001/jama.297.15.1683

Scientific article

Review

English

Clinical response and risk for reported suicidal ideation and suicide attempts in pediatric antidepressant treatment: a meta-analysis of randomized controlled trials

ContributorsBridge, Jeffrey; Iyengar, Satish; Salary, Cheryl B; Barbe, Remy; Birmaher, Boris; Pincus, Harold Alan; Ren, Lulu; Brent, David A

Published inJAMA, vol. 297, no. 15, p. 1683-1696

Publication date2007

Abstract

The US Food and Drug Administration (FDA) has issued warnings that use of antidepressant medications poses a small but significantly increased risk of suicidal ideation/suicide attempt for children and adolescents.

Keywords

Adolescent
Antidepressive Agents, Second-Generation/adverse effects/therapeutic use
Anxiety Disorders/drug therapy
Child
Depressive Disorder, Major/drug therapy
Humans
Obsessive-Compulsive Disorder/drug therapy
Randomized Controlled Trials as Topic
Risk
Suicide/psychology/statistics & numerical data
Suicide, Attempted/psychology/statistics & numerical data

Affiliation entities

Citation (ISO format)

BRIDGE, Jeffrey et al. Clinical response and risk for reported suicidal ideation and suicide attempts in pediatric antidepressant treatment: a meta-analysis of randomized controlled trials. In: JAMA, 2007, vol. 297, n° 15, p. 1683–1696. doi: 10.1001/jama.297.15.1683

Article (Published version)

Identifiers

PID : unige:43111
DOI : 10.1001/jama.297.15.1683
PMID : 17440145

Journal ISSN0098-7484

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Clinical response and risk for reported suicidal ideation and suicide attempts in pediatric antidepressant treatment: a meta-analysis of randomized controlled trials

The US Food and Drug Administration (FDA) has issued warnings that use of antidepressant medications poses a small but significantly increased risk of suicidal ideation/suicide attempt for children and adolescents.

Technical informations