Th17 cells favor inflammatory responses while inhibiting type I collagen deposition by dermal fibroblasts: differential effects in healthy and systemic sclerosis fibroblasts
Published inArthritis research & therapy, vol. 15, no. 5, R151
Publication date2013
Abstract
Keywords
- Blotting, Western
- Cells, Cultured
- Chemokine CCL2/genetics/metabolism
- Collagen Type I/genetics/metabolism
- Culture Media, Conditioned/metabolism/pharmacology
- Dose-Response Relationship, Drug
- Enzyme-Linked Immunosorbent Assay
- Female
- Fibroblasts/drug effects/metabolism
- Gene Expression/drug effects
- Humans
- Inflammation Mediators/metabolism
- Interferon-gamma/pharmacology
- Interleukin-17/pharmacology
- Interleukin-8/genetics/metabolism
- Male
- Matrix Metalloproteinase 1/genetics/metabolism
- Radioimmunoassay
- Reverse Transcriptase Polymerase Chain Reaction
- Scleroderma, Systemic/genetics/metabolism/pathology
- Skin/metabolism/pathology
- Th17 Cells/metabolism
- Tumor Necrosis Factor-alpha/pharmacology
Research group
Citation (ISO format)
BREMBILLA, Nicolo et al. Th17 cells favor inflammatory responses while inhibiting type I collagen deposition by dermal fibroblasts: differential effects in healthy and systemic sclerosis fibroblasts. In: Arthritis research & therapy, 2013, vol. 15, n° 5, p. R151. doi: 10.1186/ar4334
Main files (1)
Article (Published version)
Identifiers
- PID : unige:42797
- DOI : 10.1186/ar4334
- PMID : 24289089
ISSN of the journal1478-6354
