• Home
  1. Home
  2. Comparison of high gamma electrocorticography and fMRI with electrocortical stimulation for localization of somatosensory and language cortex
Scientific article
English

Comparison of high gamma electrocorticography and fMRI with electrocortical stimulation for localization of somatosensory and language cortex

Contributors

Genetti Gatfield, Mélanie; Tyrand, Rémi; Grouiller, Frédéric; Lascano, Agustina Maria; Vulliemoz, Serge; Spinelli, Laurent Jean-François; Seeck, Margitta; Schaller, Karl Lothard; Michel, Christoph

Published in

Clinical neurophysiology, vol. 126, no. 1, p. 121-130

Publication date

2015

Abstract

We investigated the contribution of electrocortical stimulation (ECS), induced high gamma electrocorticography (hgECoG) and functional magnetic resonance imaging (fMRI) for the localization of somatosensory and language cortex. 23 Epileptic patients with subdural electrodes underwent a protocol of somatosensory stimulation and/or an auditory semantic decision task. 14 Patients did the same protocol with fMRI prior to implantation. ECS resulted in the identification of thumb somatosensory cortex in 12/16 patients. Taking ECS as a gold standard, hgECoG and fMRI identified 53.6/33% of true positive and 4/12% of false positive contacts, respectively. The hgECoG false positive sites were all found in the hand area of the post-central gyrus. ECS localized language-related sites in 7/12 patients with hgECoG and fMRI showing 50/64% of true positive and 8/23% of false positive contacts, respectively. All but one of the hgECoG/fMRI false positive contacts were located in plausible language areas. Four patients showed post-surgical impairments: the resection included the sites positively indicated by ECS, hgECoG and fMRI in 3 patients and a positive hgECoG site in one patient. HgECoG and fMRI provide additional localization information in patients who cannot sufficiently collaborate during ECS. HgECoG and fMRI make the cortical mapping procedure more flexible not only by identifying priority cortical sites for ECS or when ECS is not feasible, but also when ECS does not provide any result.

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

GENETTI GATFIELD, Mélanie et al. Comparison of high gamma electrocorticography and fMRI with electrocortical stimulation for localization of somatosensory and language cortex. In: Clinical neurophysiology, 2015, vol. 126, n° 1, p. 121–130. doi: 10.1016/j.clinph.2014.04.007

Main files (1)

Article (Published version)

Identifiers

Journal ISSN

1388-2457
832views
0downloads

Technical informations

Creation

20/10/2014 09:49:00

First validation

20/10/2014 09:49:00

Update

14/03/2023 22:21:15

Status update

14/03/2023 22:21:15

Last indexation

09/02/2025 15:48:32
All rights reserved by Archive ouverte UNIGE and the University of Geneva
OpenAIRE Indexed & Validated