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Scientific article
Open access
English

GPCRDB: an information system for G protein-coupled receptors

Published inNucleic acids research, vol. 26, no. 1, p. 275-279
Publication date1998
Abstract

The GPCRDB is a G protein-coupled receptor (GPCR) database system aimed at the collection and dissemination of GPCR related data. It holds sequences, mutant data and ligand binding constants as primary (experimental) data. Computationally derived data such as multiple sequence alignments, three dimensional models, phylogenetic trees and two dimensional visualization tools are added to enhance the database's usefulness. The GPCRDB is an EU sponsored project aimed at building a generic molecular class specific database capable of dealing with highly heterogeneous data. GPCRs were chosen as test molecules because of their enormous importance for medical sciences and due to the availability of so much highly heterogeneous data. The GPCRDB is available via the WWW at http://www.gpcr.org/7tm

Keywords
  • Computer Communication Networks
  • Databases, Factual
  • GTP-Binding Proteins/metabolism
  • Humans
  • Information Storage and Retrieval
  • Information Systems
  • Receptors, Cell Surface/metabolism
Citation (ISO format)
HORN, Florence et al. GPCRDB: an information system for G protein-coupled receptors. In: Nucleic acids research, 1998, vol. 26, n° 1, p. 275–279. doi: 10.1093/nar/26.1.275
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Article (Published version)
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ISSN of the journal0305-1048
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