GPCRDB: an information system for G protein-coupled receptors

Horn, Florence; Weare, J; Beukers, M W; Hörsch, S; Bairoch, Amos Marc; Chen, W; Edvardsen, O; Campagne, F; Vriend, Gert

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Title		GPCRDB: an information system for G protein-coupled receptors
Authors		Horn, Florence Weare, J Beukers, M W Hörsch, S Bairoch, Amos Marc Chen, W Edvardsen, O Campagne, F Vriend, Gert show all authors [1 - 9]
Published in		Nucleic Acids Research. 1998, vol. 26, no. 1, p. 275-9
Abstract		The GPCRDB is a G protein-coupled receptor (GPCR) database system aimed at the collection and dissemination of GPCR related data. It holds sequences, mutant data and ligand binding constants as primary (experimental) data. Computationally derived data such as multiple sequence alignments, three dimensional models, phylogenetic trees and two dimensional visualization tools are added to enhance the database's usefulness. The GPCRDB is an EU sponsored project aimed at building a generic molecular class specific database capable of dealing with highly heterogeneous data. GPCRs were chosen as test molecules because of their enormous importance for medical sciences and due to the availability of so much highly heterogeneous data. The GPCRDB is available via the WWW at http://www.gpcr.org/7tm
Keywords		Computer Communication Networks — Databases, Factual — GTP-Binding Proteins/metabolism — Humans — Information Storage and Retrieval — Information Systems — Receptors, Cell Surface/metabolism
Identifiers		DOI: 10.1093/nar/26.1.275 PMID: 9399852
Full text		Article (Published version) (259 Kb) - Free access Other version: http://nar.oxfordjournals.org/content/26/1/275.long
Structures		Faculté de médecine / Section de médecine fondamentale / Département de biologie structurale et bioinformatique
Research groups		Calipho (80) Swiss-Prot Research Group Swiss Institute of Bioinformatics
Citation (ISO format)		HORN, Florence et al. GPCRDB: an information system for G protein-coupled receptors. In: Nucleic Acids Research, 1998, vol. 26, n° 1, p. 275-9. https://archive-ouverte.unige.ch/unige:42477