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Title

Genetic interactions between the genes encoding the Elba complex and the Fab-7 boundary

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Director
Denomination Master en biologie orientation Génétique Développement et Evolution
Defense Maîtrise : Univ. Genève, 2014
Abstract The aim of my master project has been to look for genetic interactions between mutations of the genes encoding the Elba complex and the Fab-7 boundary that is crippled by the mutations in the 5 GAGAG sites of HS1. Knowing that phenotypes caused by mutations can be hidden by maternal contribution and that the mutant we recovered are not homozygous viable, I have also generated mutant flies in which the genes are inactivated by RNAi. Using this method combined with a Fab-7 boundary mutant for its GAGAG binding sites within HS1, I observed an aggravation of the Fab-7 phenotype with high penetrance with every gene inactivation.
Keywords Bithorax Complex (BX-C)Fab-7
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Research group Groupe Karch
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ROSSIER, Mikaël. Genetic interactions between the genes encoding the Elba complex and the Fab-7 boundary. Université de Genève. Maîtrise, 2014. https://archive-ouverte.unige.ch/unige:42310

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Deposited on : 2014-12-01

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