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Title

5-Fluorouracil as protracted continuous intravenous infusion can be added to full-dose docetaxel (Taxotere)-cisplatin in advanced gastric carcinoma: a phase I-II trial

Authors
Maibach, R
Fazio, N
Sessa, C
Stupp, R
Morant, R
Herrmann, R
Borner, M M
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Published in Annals of Oncology. 2004, vol. 15, no. 5, p. 759-64
Abstract A phase I-II multicenter trial was conducted to define the maximum tolerated dose (MTD) according to tolerance and toxicity (primary objective), as well as to describe the clinical activity, in terms of response and survival (secondary objectives), of a combination of 5-fluorouracil (5-FU) in protracted continuous intravenous infusion (p.i.v.) with docetaxel and cisplatin for patients with advanced gastric cancer.
Keywords AdultAgedAntineoplastic Combined Chemotherapy Protocols/therapeutic useCarcinoma/drug therapy/pathologyCisplatin/administration & dosageFemaleFluorouracil/administration & dosageHumansInfusions, IntravenousMaleMaximum Tolerated DoseMiddle AgedStomach Neoplasms/drug therapy/pathologySurvival AnalysisTaxoids/administration & dosage
Identifiers
PMID: 15111343
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Research group Groupe Roth Arnaud (oncologie) (285)
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ROTH, Arnaud et al. 5-Fluorouracil as protracted continuous intravenous infusion can be added to full-dose docetaxel (Taxotere)-cisplatin in advanced gastric carcinoma: a phase I-II trial. In: Annals of Oncology, 2004, vol. 15, n° 5, p. 759-64. https://archive-ouverte.unige.ch/unige:42140

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Deposited on : 2014-11-24

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