We investigate the two-dimensional Fermi surface of high-mobility LaAlO3/ SrTiO3 interfaces using Shubnikov-de Haas oscillations. Our analysis of the oscillation pattern underscores the key role played by the Rashba spin–orbit interaction brought about by the breaking of inversion symmetry, as well as the dominant contribution of the heavy dxz/dyz orbitals on electrical transport. We furthermore bring into light the complex evolution of the oscillations with the carrier density, which is tuned by the field effect.