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Title

Acute vascular rejection of xenografts: roles of natural and elicited xenoreactive antibodies in activation of vascular endothelial cells and induction of procoagulant activity

Authors
Gollackner, Bernd
Goh, Seo Kiat
Qawi, Imrana
Knosalla, Christoph
Daniel, Soizic
Kaczmarek, Elzbieta
Awwad, Michel
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Published in Transplantation. 2004, vol. 77, no. 11, p. 1735-41
Abstract Hyperacute rejection of vascularized discordant xenografts can now be effectively managed. However, acute vascular rejection (AVR) then ensues, resulting in graft destruction, coagulopathy, or both within weeks. The aim of this study was to determine associations between humoral responses to the xenograft and the induction of AVR, coagulopathy, or both.
Keywords Acute DiseaseAnimalsAntibodies, Heterophile/immunologyAortaBloodBlood Coagulation Disorders/immunologyCells, CulturedEndothelium, Vascular/drug effects/immunology/metabolismGraft Rejection/pathologyImmunizationKidney TransplantationPapioPlant Lectins/pharmacologySwineThromboplastin/metabolismTransplantation, Heterologous
Identifiers
PMID: 15201675
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Structures
Research group Chirurgie viscérale (104)
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GOLLACKNER, Bernd et al. Acute vascular rejection of xenografts: roles of natural and elicited xenoreactive antibodies in activation of vascular endothelial cells and induction of procoagulant activity. In: Transplantation, 2004, vol. 77, n° 11, p. 1735-41. https://archive-ouverte.unige.ch/unige:41704

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Deposited on : 2014-11-12

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