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Detection of intrahepatic hepatitis C virus replication by strand-specific semi-quantitative RT-PCR: preliminary application to the liver transplantation model

Publié dansJournal of hepatology, vol. 29, no. 1, p. 1-11
Date de publication1998
Résumé

Although the hepatitis C virus infection recurs in virtually all patients after liver transplantation, up to 50% of patients may not have histological recurrent hepatitis 1 year after liver transplantation. To study the relationship between hepatitis C virus infection and liver disease after liver transplantation, we compared the intrahepatic hepatitis C virus replication levels with the liver histopathology among liver transplant recipients.

Mots-clés
  • Adult
  • Female
  • Hepacivirus/isolation & purification/physiology
  • Hepatitis C/pathology/surgery
  • Hepatitis C Antigens/analysis
  • Humans
  • Liver Transplantation/pathology
  • Male
  • Middle Aged
  • Polymerase Chain Reaction/methods
  • RNA, Viral/analysis
  • Recurrence
  • Sensitivity and Specificity
  • Virus Replication
Citation (format ISO)
NEGRO, Francesco et al. Detection of intrahepatic hepatitis C virus replication by strand-specific semi-quantitative RT-PCR: preliminary application to the liver transplantation model. In: Journal of hepatology, 1998, vol. 29, n° 1, p. 1–11. doi: 10.1016/S0168-8278(98)80172-4
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Article (Published version)
accessLevelRestricted
Identifiants
ISSN du journal0168-8278
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Création30.10.2014 11:55:00
Première validation30.10.2014 11:55:00
Heure de mise à jour14.03.2023 22:12:34
Changement de statut14.03.2023 22:12:34
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