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Title

Résultats d'un programme de transplantation hépatique combiné adultes-enfants en Suisse

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Published in Schweizerische medizinische Wochenschrift. 1999, vol. 129, no. 11, p. 433-40
Abstract Between July 1987 and August 1998, 173 orthotopic liver transplantations (OLT) were performed in Geneva. We studied a homogeneous group of 114 OLT performed during the 6 years between 1992 and 1997 on 107 patients (89 adults and 18 children; 7 retransplantations). Although Geneva has the largest transplantation programme in Switzerland and is the only centre performing paediatric liver transplantation, the mean number of procedures per year was 19, corresponding to only a small transplantation programme in Europe. It could be reasonably questioned, therefore, whether Swiss patients are not at a disadvantage as compared with patients from European countries with larger liver transplantation centres. Although the perioperative morbidity was still considerable, the results of this series -90% of actuarial patient survival at 1 and 2 years and 84% at 5 years-compare favourably with the results of the European Liver Transplantation Registry: 76% of actuarial patient survival at 1 year and 65% at 5 years. In this series, 95 patients (89%) were alive on January 1, 1998. As no patient was refused on the severity of the liver disease and as more than 10% of OLT were performed as emergencies, a bias due to the selection of the best cases cannot explain the good results. This series demonstrates that a small liver transplantation centre may obtain results that compare favourably with the results of large European centres, and that Swiss patients are not at a disadvantage as compared with patients of other European countries.
Keywords AdultChildEuropeGraft Rejection/epidemiologyHumansLiver Diseases/classification/surgeryLiver Transplantation/mortality/physiology/statistics & numerical dataPostoperative ComplicationsRegistriesReoperationRetrospective StudiesSurvival RateSwitzerlandTime FactorsTissue and Organ Procurement/organization & administration
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PMID: 10226324
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Research groups Hépatologie chirurgicale (327)
Métastases du foie (657)
Chirurgie viscérale (104)
Gastroentérologie et transplantation (pédiatrie) (181)
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(ISO format)
MENTHA, Gilles et al. Résultats d'un programme de transplantation hépatique combiné adultes-enfants en Suisse. In: Schweizerische medizinische Wochenschrift, 1999, vol. 129, n° 11, p. 433-40. https://archive-ouverte.unige.ch/unige:41204

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Deposited on : 2014-10-27

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