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Scientific article
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French

Résultats d'un programme de transplantation hépatique combiné adultes-enfants en Suisse

Published inSchweizerische medizinische Wochenschrift, vol. 129, no. 11, p. 433-440
Publication date1999
Abstract

Between July 1987 and August 1998, 173 orthotopic liver transplantations (OLT) were performed in Geneva. We studied a homogeneous group of 114 OLT performed during the 6 years between 1992 and 1997 on 107 patients (89 adults and 18 children; 7 retransplantations). Although Geneva has the largest transplantation programme in Switzerland and is the only centre performing paediatric liver transplantation, the mean number of procedures per year was 19, corresponding to only a small transplantation programme in Europe. It could be reasonably questioned, therefore, whether Swiss patients are not at a disadvantage as compared with patients from European countries with larger liver transplantation centres. Although the perioperative morbidity was still considerable, the results of this series -90% of actuarial patient survival at 1 and 2 years and 84% at 5 years-compare favourably with the results of the European Liver Transplantation Registry: 76% of actuarial patient survival at 1 year and 65% at 5 years. In this series, 95 patients (89%) were alive on January 1, 1998. As no patient was refused on the severity of the liver disease and as more than 10% of OLT were performed as emergencies, a bias due to the selection of the best cases cannot explain the good results. This series demonstrates that a small liver transplantation centre may obtain results that compare favourably with the results of large European centres, and that Swiss patients are not at a disadvantage as compared with patients of other European countries.

Keywords
  • Adult
  • Child
  • Europe
  • Graft Rejection/epidemiology
  • Humans
  • Liver Diseases/classification/surgery
  • Liver Transplantation/mortality/physiology/statistics & numerical data
  • Postoperative Complications
  • Registries
  • Reoperation
  • Retrospective Studies
  • Survival Rate
  • Switzerland
  • Time Factors
  • Tissue and Organ Procurement/organization & administration
Citation (ISO format)
MENTHA, Gilles et al. Résultats d’un programme de transplantation hépatique combiné adultes-enfants en Suisse. In: Schweizerische medizinische Wochenschrift, 1999, vol. 129, n° 11, p. 433–440.
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ISSN of the journal0036-7672
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