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Scientific article
English

Hepatocyte steatosis is a cytopathic effect of hepatitis C virus genotype 3

Published inJournal of hepatology, vol. 33, no. 1, p. 106-115
Publication date2000
Abstract

Patients infected with the hepatitis C virus (HCV) often have liver steatosis, suggesting the possibility of a viral cytopathic effect. The aim of this study was to correlate the occurrence and severity of liver steatosis with HCV RNA type, level and sequence of the core-encoding region.

Keywords
  • Adult
  • Aged
  • Amino Acid Sequence/genetics
  • Antiviral Agents/therapeutic use
  • Fatty Liver/virology
  • Female
  • Genotype
  • Hepacivirus/genetics
  • Hepatitis C, Chronic/complications/immunology/pathology/virology
  • Humans
  • Immunocompetence
  • Interferon-alpha/therapeutic use
  • Liver Cirrhosis/drug therapy/virology
  • Liver Transplantation
  • Male
  • Middle Aged
  • Molecular Sequence Data
  • Nucleocapsid Proteins/genetics
  • RNA, Viral/genetics
Citation (ISO format)
RUBBIA-BRANDT, Laura et al. Hepatocyte steatosis is a cytopathic effect of hepatitis C virus genotype 3. In: Journal of hepatology, 2000, vol. 33, n° 1, p. 106–115. doi: 10.1016/S0168-8278(00)80166-X
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Article (Published version)
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Identifiers
ISSN of the journal0168-8278
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First validation10/21/2014 11:42:00 AM
Update time03/14/2023 10:03:21 PM
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