Scientific article
English

Efficacy and safety of tacrolimus compared with cyclosporine microemulsion in primary simultaneous pancreas-kidney transplantation: 1-year results of a large multicenter trial

Published inTransplantation, vol. 77, no. 8, p. 1221-1228
Publication date2004
Abstract

Simultaneous pancreas-kidney transplantation (SPK) transplantation has become an accepted therapy for type 1 diabetic patients with end-stage renal disease. This open-label, multicenter study compared the efficacy and safety of tacrolimus with the microemulsion (ME) formulation of cyclosporine in a clinical setting. The 1-year results are reported here.

Keywords
  • Acute Disease
  • Adult
  • Cyclosporine/administration & dosage/adverse effects/therapeutic use
  • Diabetes Mellitus, Type 1/surgery
  • Diabetic Nephropathies/surgery
  • Emulsions
  • Europe
  • Female
  • Graft Rejection/prevention & control
  • Graft Survival/drug effects
  • Humans
  • Immunosuppressive Agents/administration & dosage/adverse effects/therapeutic use
  • Israel
  • Kidney Transplantation/immunology
  • Male
  • Middle Aged
  • Pancreas Transplantation/immunology
  • Safety
  • Tacrolimus/adverse effects/therapeutic use
Citation (ISO format)
BECHSTEIN, Wolf Otto et al. Efficacy and safety of tacrolimus compared with cyclosporine microemulsion in primary simultaneous pancreas-kidney transplantation: 1-year results of a large multicenter trial. In: Transplantation, 2004, vol. 77, n° 8, p. 1221–1228. doi: 10.1097/01.tp.0000120865.96360.df
Main files (1)
Article (Accepted version)
accessLevelRestricted
Identifiers
Journal ISSN0041-1337
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