en
Scientific article
English

No complement receptor 1 stumps on podocytes in human glomerulopathies

Published inKidney international, vol. 59, no. 1, p. 160-168
Publication date2001
Abstract

Type one complement receptor (CR1) is the only physiological inhibitor of complement on podocytes. CR1 is lost in different glomerulopathies, in particular in lupus nephritis, in which it has been suggested that CR1 is removed by proteolysis from the cell membrane.

Keywords
  • Antibodies, Monoclonal
  • Epithelial Cells/metabolism
  • Glomerulonephritis, IGA/metabolism/pathology
  • Glomerulonephritis, Membranous/metabolism/pathology
  • Humans
  • Immunohistochemistry
  • Kidney Diseases/metabolism/pathology
  • Kidney Glomerulus/metabolism/pathology
  • Lupus Nephritis/metabolism/pathology
  • Nephritis/metabolism/pathology
  • Nephrosis, Lipoid/metabolism/pathology
  • Receptors, Complement 3b/metabolism
  • Reference Values
Affiliation Not a UNIGE publication
Citation (ISO format)
MOLL, Solange et al. No complement receptor 1 stumps on podocytes in human glomerulopathies. In: Kidney international, 2001, vol. 59, n° 1, p. 160–168. doi: 10.1046/j.1523-1755.2001.00476.x
Main files (1)
Article (Accepted version)
accessLevelRestricted
Identifiers
ISSN of the journal0085-2538
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