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No complement receptor 1 stumps on podocytes in human glomerulopathies

Miot, S
Gudat, F
Mihatsch, M J
Schifferli, J A
Published in Kidney International. 2001, vol. 59, no. 1, p. 160-8
Abstract Type one complement receptor (CR1) is the only physiological inhibitor of complement on podocytes. CR1 is lost in different glomerulopathies, in particular in lupus nephritis, in which it has been suggested that CR1 is removed by proteolysis from the cell membrane.
Keywords Antibodies, MonoclonalEpithelial Cells/metabolismGlomerulonephritis, IGA/metabolism/pathologyGlomerulonephritis, Membranous/metabolism/pathologyHumansImmunohistochemistryKidney Diseases/metabolism/pathologyKidney Glomerulus/metabolism/pathologyLupus Nephritis/metabolism/pathologyNephritis/metabolism/pathologyNephrosis, Lipoid/metabolism/pathologyReceptors, Complement 3b/metabolismReference Values
PMID: 11135068
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MOLL, Solange et al. No complement receptor 1 stumps on podocytes in human glomerulopathies. In: Kidney International, 2001, vol. 59, n° 1, p. 160-8.

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Deposited on : 2014-10-13

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