Many alpha-proteobacteria divide asymmetrically, but this process was mostly described in Caulobacter crescentus. At each cell division, a stalked and a swarmer daughter cell are produced. The swarmer daughter cell is motile and possesses a polar flagellum and several pili bunched at the flagellated pole. This cell is often referred to the G1-like phase.The stalked cell is characterized by a cell extension, the stalk, and the adhesive holdfast at its tip that is essential for irreversible attachment to surfaces. Only this cell type is able to replicate its chromosome and resides in the S-phase. My thesis work consists in identifying new transcriptional regulators involved in the different cell cycle transitions.