UNIGE document Scientific Article
previous document  unige:40329  next document
add to browser collection
Title

Activity-dependent structural plasticity of perisynaptic astrocytic domains promotes excitatory synapse stability

Authors
Janett, Elia
Jones, Emma Victoria
Murai, Keith K
show hidden authors show all authors [1 - 11]
Published in Current Biology. 2014, vol. 24, no. 15, p. 1679-88
Abstract Excitatory synapses in the CNS are highly dynamic structures that can show activity-dependent remodeling and stabilization in response to learning and memory. Synapses are enveloped with intricate processes of astrocytes known as perisynaptic astrocytic processes (PAPs). PAPs are motile structures displaying rapid actin-dependent movements and are characterized by Ca(2+) elevations in response to neuronal activity. Despite a debated implication in synaptic plasticity, the role of both Ca(2+) events in astrocytes and PAP morphological dynamics remain unclear.
Identifiers
PMID: 25042585
Full text
Article (Published version) (281 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Research group Plasticité des synapses excitatrices (76)
Citation
(ISO format)
BERNARDINELLI, Yann et al. Activity-dependent structural plasticity of perisynaptic astrocytic domains promotes excitatory synapse stability. In: Current Biology, 2014, vol. 24, n° 15, p. 1679-88. https://archive-ouverte.unige.ch/unige:40329

274 hits

2 downloads

Update

Deposited on : 2014-09-18

Export document
Format :
Citation style :