• Home
  1. Home
  2. Time course of lung injury in rat acute pancreatitis
Scientific article
OA Policy
English

Time course of lung injury in rat acute pancreatitis

Contributors

Morel, Denis; Frossard, Jean-Louis; Cikirikcioglu, Banu; Tapponnier, Maxime; Pastor, Catherine

Published in

Intensive care medicine, vol. 32, no. 11, p. 1872-1880

Publication date

2006

Abstract

Lung injury is a severe complication of acute pancreatitis that increases the mortality rate of the disease. The pathophysiology of acute pancreatitis has been studied in several experimental models, but the kinetics of pulmonary complications in relation to the pancreatic disease is not completely understood. We then studied the severity of acute pancreatitis-associated lung injury over 18h in rats that had taurocholic acid injection in the pancreatic duct and determined whether blood collected from rats with pancreatitis is toxic enough to induce injury in normal lungs.

Keywords

  • Acute Disease
  • Animals
  • Disease Progression
  • Pancreatitis/blood/complications
  • Prospective Studies
  • Random Allocation
  • Rats
  • Rats, Sprague-Dawley
  • Respiratory Distress Syndrome, Adult/etiology/physiopathology
  • Taurocholic Acid
  • Time Factors

UNIGE affiliation entities

UNIGE research groups

Funding

  • Swiss National Science Foundation - 3200-100868
  • Swiss National Science Foundation - 3200-100764

Citation (ISO format)

MOREL, Denis et al. Time course of lung injury in rat acute pancreatitis. In: Intensive care medicine, 2006, vol. 32, n° 11, p. 1872–1880. doi: 10.1007/s00134-006-0264-9

Main files (1)

Article (Published version)

Identifiers

Journal ISSN

0342-4642
652views
491downloads

Technical informations

Creation

06/08/2014 10:29:00

First validation

06/08/2014 10:29:00

Update

14/03/2023 21:46:26

Status update

14/03/2023 21:46:26

Last indexation

30/10/2024 20:04:30
All rights reserved by Archive ouverte UNIGE and the University of Geneva
OpenAIRE Indexed & Validated