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Time course of lung injury in rat acute pancreatitis

Cikirikcioglu, Banu
Tapponnier, Maxime
Published in Intensive Care Medicine. 2006, vol. 32, no. 11, p. 1872-80
Abstract Lung injury is a severe complication of acute pancreatitis that increases the mortality rate of the disease. The pathophysiology of acute pancreatitis has been studied in several experimental models, but the kinetics of pulmonary complications in relation to the pancreatic disease is not completely understood. We then studied the severity of acute pancreatitis-associated lung injury over 18h in rats that had taurocholic acid injection in the pancreatic duct and determined whether blood collected from rats with pancreatitis is toxic enough to induce injury in normal lungs.
Keywords Acute DiseaseAnimalsDisease ProgressionPancreatitis/blood/complicationsProspective StudiesRandom AllocationRatsRats, Sprague-DawleyRespiratory Distress Syndrome, Adult/etiology/physiopathologyTaurocholic AcidTime Factors
PMID: 16845510
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Article (Published version) (480 Kb) - public document Free access
Research group Pharmacologie et imagerie du foie (664)
FNS: 3200-100868
FNS: 3200-100764
(ISO format)
MOREL, Denis et al. Time course of lung injury in rat acute pancreatitis. In: Intensive Care Medicine, 2006, vol. 32, n° 11, p. 1872-80. doi: 10.1007/s00134-006-0264-9 https://archive-ouverte.unige.ch/unige:40290

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Deposited on : 2014-09-18

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