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Title

Effect of emaciation and obesity on small-animal internal radiation dosimetry for positron-emitting radionuclides

Authors
Published in European Journal of Nuclear Medicine and Molecular Imaging. 2013, vol. 40, no. 11, p. 1748-59
Abstract Rats are widely used in biomedical research involving molecular imaging and therefore the radiation dose to animals has become a concern. The weight of laboratory animals might change through emaciation or obesity as a result of their use in various research experiments including those investigating different diet types. In this work, we evaluated the effects of changes in body weight induced by emaciation and obesity on the internal radiation dose from common positron-emitting radionuclides.
Keywords AnimalsElectronsEmaciation/radionuclide imagingModels, BiologicalObesity/radionuclide imagingRadioisotopes/pharmacokineticsRadiometryRatsTissue Distribution
Identifiers
PMID: 23817685
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Article (Published version) (1.3 MB) - public document Free access
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Research group Imagerie Médicale (TEP et TEMP) (542)
Project FNS: 31003A-149957
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(ISO format)
XIE, Tianwu, ZAIDI, Habib. Effect of emaciation and obesity on small-animal internal radiation dosimetry for positron-emitting radionuclides. In: European Journal of Nuclear Medicine and Molecular Imaging, 2013, vol. 40, n° 11, p. 1748-59. https://archive-ouverte.unige.ch/unige:40171

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Deposited on : 2014-09-12

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