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Title

Effect of emaciation and obesity on small-animal internal radiation dosimetry for positron-emitting radionuclides
Authors
Xie, Tianwu
Zaidi, Habib
Published in European Journal of Nuclear Medicine and Molecular Imaging. 2013, vol. 40, no. 11, p. 1748-59
Abstract Rats are widely used in biomedical research involving molecular imaging and therefore the radiation dose to animals has become a concern. The weight of laboratory animals might change through emaciation or obesity as a result of their use in various research experiments including those investigating different diet types. In this work, we evaluated the effects of changes in body weight induced by emaciation and obesity on the internal radiation dose from common positron-emitting radionuclides.
Keywords Animals — Electrons — Emaciation/radionuclide imaging — Models, Biological — Obesity/radionuclide imaging — Radioisotopes/pharmacokinetics — Radiometry — Rats — Tissue Distribution
Identifiers
PMID: 23817685
Full text
Article (Published version) (1.3 MB) - public document Free access
Structures
Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale
Research group Imagerie Médicale (TEP et TEMP) (542)
Project FNS: 31003A-149957
Citation
(ISO format) 		XIE, Tianwu, ZAIDI, Habib. Effect of emaciation and obesity on small-animal internal radiation dosimetry for positron-emitting radionuclides. In: European Journal of Nuclear Medicine and Molecular Imaging, 2013, vol. 40, n° 11, p. 1748-59. https://archive-ouverte.unige.ch/unige:40171

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Deposited on : 2014-09-12

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