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Upregulation of CD40, CD80, CD83 or CD86 on alveolar macrophages after lung transplantation

Published in The Journal of heart and lung transplantation. 2005, vol. 24, no. 8, p. 1067-75
Abstract Alveolar macrophages (AMs) are known to be poor antigen-presenting cells, and lack the accessory molecules such as CD40, CD80 or CD86 to activate T cells. The question raised is about the potential changes in phenotypes after lung transplantation, particularly during acute rejection episodes.
Keywords AdultAgedAntigens, CD/analysisAntigens, CD40/analysisAntigens, CD86/analysisBiological Markers/analysisBronchoalveolar Lavage Fluid/cytologyCase-Control StudiesFemaleFlow CytometryGraft RejectionGraft SurvivalHumansImmunoglobulins/analysisImmunohistochemistryLung Transplantation/adverse effects/immunologyMacrophages, Alveolar/cytologyMaleMembrane Glycoproteins/analysisMiddle AgedPrognosisReference ValuesRetrospective StudiesSensitivity and SpecificityTransplantation Immunology/physiologyUp-Regulation
PMID: 16102442
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Research group Groupe Pache Jean-Claude (pathologie clinique) (658)
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NICOD, Laurent et al. Upregulation of CD40, CD80, CD83 or CD86 on alveolar macrophages after lung transplantation. In: The Journal of heart and lung transplantation, 2005, vol. 24, n° 8, p. 1067-75. doi: 10.1016/j.healun.2004.07.011 https://archive-ouverte.unige.ch/unige:39992

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Deposited on : 2014-09-05

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