I.v. N-acetylcysteine and emergency CT: use of serum creatinine and cystatin C as markers of radiocontrast nephrotoxicity

Poletti, Pierre-Alexandre Alois; Saudan, Patrick; Platon, Alexandra; Mermillod, Bernadette; Sautter, Anna Maria; Vermeulen, Bernard; Sarasin, François; Becker, Christoph; Martin, Pierre-Yves

doi:10.2214/AJR.07.2356

Scientific article

English

I.v. N-acetylcysteine and emergency CT: use of serum creatinine and cystatin C as markers of radiocontrast nephrotoxicity

ContributorsPoletti, Pierre-Alexandre Alois; Saudan, Patrick; Platon, Alexandra; Mermillod, Bernadette; Sautter, Anna Maria; Vermeulen, Bernard; Sarasin, François; Becker, Christoph; Martin, Pierre-Yves

Published inAmerican journal of roentgenology, vol. 189, no. 3, p. 687-692

Publication date2007

Abstract

The purpose of this study was to assess the effect of i.v. administration of N-acetylcysteine (NAC) on serum levels of creatinine and cystatin C, two markers of renal function, in patients with renal insufficiency who undergo emergency contrast-enhanced CT.

Keywords

Acetylcysteine/administration & dosage
Acute Kidney Injury/blood/chemically induced/prevention & control
Adult
Biological Markers/blood
Contrast Media/adverse effects
Creatinine/blood
Cystatin C
Cystatins/blood
Emergency Medical Services/methods
Female
Humans
Injections, Intravenous/adverse effects
Iohexol/adverse effects/analogs & derivatives/diagnostic use
Male
Tomography, X-Ray Computed/adverse effects
Treatment Outcome

Affiliation entities

Research groups

Citation (ISO format)

POLETTI, Pierre-Alexandre Alois et al. I.v. N-acetylcysteine and emergency CT: use of serum creatinine and cystatin C as markers of radiocontrast nephrotoxicity. In: American journal of roentgenology, 2007, vol. 189, n° 3, p. 687–692. doi: 10.2214/AJR.07.2356

Article (Published version)

Identifiers

PID : unige:39629
DOI : 10.2214/AJR.07.2356
PMID : 17715118

Journal ISSN0361-803X

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I.v. N-acetylcysteine and emergency CT: use of serum creatinine and cystatin C as markers of radiocontrast nephrotoxicity

The purpose of this study was to assess the effect of i.v. administration of N-acetylcysteine (NAC) on serum levels of creatinine and cystatin C, two markers of renal function, in patients with renal insufficiency who undergo emergency contrast-enhanced CT.

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