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Title

A randomized phase II trial of capecitabine and two different schedules of irinotecan in first-line treatment of metastatic colorectal cancer: efficacy, quality-of-life and toxicity

Authors
Borner, M M
Bernhard, Jacqueline Simone
Popescu, R
Wernli, Marie
Saletti, P
Rauch, D
Herrmann, R
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Published in Annals of Oncology. 2005, vol. 16, no. 2, p. 282-8
Abstract To determine the efficacy, impact on quality-of-life (QoL) and tolerability of two different irinotecan administration schedules in combination with capecitabine as first-line treatment of metastatic colorectal cancer.
Keywords AdultAgedAntimetabolites, Antineoplastic/administration & dosage/adverse effects/therapeutic useAntineoplastic Agents, Phytogenic/administration & dosage/adverse effects/therapeutic useCamptothecin/administration & dosage/adverse effects/analogs & derivatives/therapeutic useColorectal Neoplasms/drug therapy/pathologyDeoxycytidine/administration & dosage/adverse effects/analogs & derivatives/therapeutic useDrug Administration ScheduleFemaleFluorouracil/analogs & derivativesHumansInfusions, IntravenousMaleMiddle AgedQuality of LifeTreatment Outcome
Identifiers
PMID: 15668285
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Article (Published version) (84 Kb) - public document Free access
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Research group Groupe Roth Arnaud (oncologie) (285)
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BORNER, M M et al. A randomized phase II trial of capecitabine and two different schedules of irinotecan in first-line treatment of metastatic colorectal cancer: efficacy, quality-of-life and toxicity. In: Annals of Oncology, 2005, vol. 16, n° 2, p. 282-8. https://archive-ouverte.unige.ch/unige:39622

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Deposited on : 2014-08-21

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