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Title

"Pseudo-Beijing": evidence for convergent evolution in the direct repeat region of Mycobacterium tuberculosis
Authors
Fenner, Lukas
Malla, Bijaya
Bescher Ninet, Béatrice Alice
Dubuis, Olivier
Stucki, David
Borrell, Sonia
Huna, Thembela
Bodmer, Thomas
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Published in PLOS ONE. 2011, vol. 6, no. 9, p. e24737
Abstract Mycobacterium tuberculosis has a global population structure consisting of six main phylogenetic lineages associated with specific geographic regions and human populations. One particular M. tuberculosis genotype known as "Beijing" has repeatedly been associated with drug resistance and has been emerging in some parts of the world. "Beijing" strains are traditionally defined based on a characteristic spoligotyping pattern. We used three alternative genotyping techniques to revisit the phylogenetic classification of M. tuberculosis complex (MTBC) strains exhibiting the typical "Beijing" spoligotyping pattern.
Keywords Biological Evolution — Genotype — Mycobacterium tuberculosis/classification/genetics — Phylogeny — Repetitive Sequences, Nucleic Acid/genetics
Identifiers
PMID: 21935448
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Article (Published version) (245 Kb) - public document Free access
Structures
Faculté de médecine / Section de médecine clinique / Département de médecine
Citation
(ISO format) 		FENNER, Lukas et al. "Pseudo-Beijing": evidence for convergent evolution in the direct repeat region of Mycobacterium tuberculosis. In: PLOS ONE, 2011, vol. 6, n° 9, p. e24737. doi: 10.1371/journal.pone.0024737 https://archive-ouverte.unige.ch/unige:39491

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Deposited on : 2014-08-18

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