en
Scientific article
Open access
English

"Pseudo-Beijing": evidence for convergent evolution in the direct repeat region of Mycobacterium tuberculosis

Published inPloS one, vol. 6, no. 9, e24737
Publication date2011
Abstract

Mycobacterium tuberculosis has a global population structure consisting of six main phylogenetic lineages associated with specific geographic regions and human populations. One particular M. tuberculosis genotype known as "Beijing" has repeatedly been associated with drug resistance and has been emerging in some parts of the world. "Beijing" strains are traditionally defined based on a characteristic spoligotyping pattern. We used three alternative genotyping techniques to revisit the phylogenetic classification of M. tuberculosis complex (MTBC) strains exhibiting the typical "Beijing" spoligotyping pattern.

Keywords
  • Biological Evolution
  • Genotype
  • Mycobacterium tuberculosis/classification/genetics
  • Phylogeny
  • Repetitive Sequences, Nucleic Acid/genetics
Citation (ISO format)
FENNER, Lukas et al. ‘Pseudo-Beijing’: evidence for convergent evolution in the direct repeat region of Mycobacterium tuberculosis. In: PloS one, 2011, vol. 6, n° 9, p. e24737. doi: 10.1371/journal.pone.0024737
Main files (1)
Article (Published version)
Identifiers
ISSN of the journal1932-6203
506views
330downloads

Technical informations

Creation08/15/2014 1:57:00 PM
First validation08/15/2014 1:57:00 PM
Update time03/14/2023 9:31:31 PM
Status update03/14/2023 9:31:31 PM
Last indexation02/12/2024 11:19:18 AM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack