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Scientific article
English

EEG alpha band synchrony predicts cognitive and motor performance in patients with ischemic stroke

Contributors

Dubovik, Sviatlana; Ptak, Radek; Aboulafia Brakha, Tatiana; Magnin, Cécile; Gillabert, Nicole; Allet, Lara; Pignat, Jean-Michel; Schnider, Armin; Guggisberg, Adrian

Published in

Behavioural neurology, vol. 26, no. 3, p. 187-189

Publication date

2013

Abstract

Functional brain networks are known to be affected by focal brain lesions. However, the clinical relevance of these changes remains unclear. This study assesses resting-state functional connectivity (FC) with electroencephalography (EEG) and relates observed topography of FC to cognitive and motor deficits in patients three months after ischemic stroke. Twenty patients (mean age 61.3 years, range 37-80, 9 females) and nineteen age-matched healthy participants (mean age 66.7 years, range 36-88, 13 females) underwent a ten-minute EEG-resting state examination. The neural oscillations at each grey matter voxel were reconstructed using an adaptive spatial filter and imaginary component of coherence (IC) was calculated as an index of FC. Maps representing mean connectivity value at each voxel were correlated with the clinical data. Compared to healthy controls, alpha band IC of stroke patients was locally reduced in brain regions critical to observed behavioral deficits. A voxel-wise Pearson correlation of clinical performances with FC yielded maps of the neural structures implicated in motor, language, and executive function. This correlation was again specific to alpha band coherence. Ischemic lesions decrease the synchrony of alpha band oscillations between affected brain regions and the rest of the brain. This decrease is linearly related to cognitive and motor deficits observed in the patients.

Keywords

  • Aged
  • Alpha Rhythm/physiology
  • Attention/physiology
  • Brain Ischemia/psychology
  • Cognition/physiology
  • Electroencephalography Phase Synchronization
  • Executive Function
  • Female
  • Functional Laterality/physiology
  • Humans
  • Male
  • Memory, Short-Term/physiology
  • Middle Aged
  • Motor Skills/physiology
  • Nerve Net/physiology
  • Nervous System Diseases/etiology/psychology
  • Predictive Value of Tests
  • Psychomotor Performance/physiology
  • Stroke/psychology
  • Verbal Behavior/physiology

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

DUBOVIK, Sviatlana et al. EEG alpha band synchrony predicts cognitive and motor performance in patients with ischemic stroke. In: Behavioural neurology, 2013, vol. 26, n° 3, p. 187–189. doi: 10.3233/BEN-2012-129007

Main files (1)

Article (Published version)

Identifiers

Journal ISSN

0953-4180
853views
7downloads

Technical informations

Creation

06/08/2014 10:11:00

First validation

06/08/2014 10:11:00

Update

14/03/2023 21:30:43

Status update

14/03/2023 21:30:42

Last indexation

30/10/2024 19:41:01
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