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Scientific article
English

Historical epidemiology of hepatitis C virus (HCV) in selected countries

Contributors

Bruggmann, P

Collaborators

Bihl, Florian; Negro, Francesco; Semela, David

Published in

Journal of viral hepatitis, vol. 21 Suppl 1, p. 5-33

Publication date

2014

Abstract

Chronic infection with hepatitis C virus (HCV) is a leading indicator for liver disease. New treatment options are becoming available, and there is a need to characterize the epidemiology and disease burden of HCV. Data for prevalence, viremia, genotype, diagnosis and treatment were obtained through literature searches and expert consensus for 16 countries. For some countries, data from centralized registries were used to estimate diagnosis and treatment rates. Data for the number of liver transplants and the proportion attributable to HCV were obtained from centralized databases. Viremic prevalence estimates varied widely between countries, ranging from 0.3% in Austria, England and Germany to 8.5% in Egypt. The largest viremic populations were in Egypt, with 6,358,000 cases in 2008 and Brazil with 2,106,000 cases in 2007. The age distribution of cases differed between countries. In most countries, prevalence rates were higher among males, reflecting higher rates of injection drug use. Diagnosis, treatment and transplant levels also differed considerably between countries. Reliable estimates characterizing HCV-infected populations are critical for addressing HCV-related morbidity and mortality. There is a need to quantify the burden of chronic HCV infection at the national level.

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

BRUGGMANN, P. Historical epidemiology of hepatitis C virus (HCV) in selected countries. In: Journal of viral hepatitis, 2014, vol. 21 Suppl 1, p. 5–33. doi: 10.1111/jvh.12247

Main files (1)

Article (Accepted version)

Identifiers

Journal ISSN

1352-0504
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Technical informations

Creation

06/08/2014 11:58:00

First validation

06/08/2014 11:58:00

Update

14/03/2023 21:30:36

Status update

14/03/2023 21:30:36

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