en
Scientific article
English

Preoperative concomitant hyperfractionated radiotherapy and gemcitabine for locally advanced rectal cancers: a phase I-II trial

Published inThe cancer journal, vol. 11, no. 2, p. 133-139
Publication date2005
Abstract

The purpose of this study was to determine the maximum tolerated dose of gemcitabine when it was administered concomitantly with hyperfractionated radiotherapy before surgery in patients with locally advanced rectal cancers and to investigate the midterm efficacy of such a regimen.

Keywords
  • Adult
  • Aged
  • Deoxycytidine/administration & dosage/adverse effects/analogs & derivatives/therapeutic use
  • Dose Fractionation
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Preoperative Care
  • Radiation-Sensitizing Agents/administration & dosage/adverse effects/therapeutic use
  • Radiotherapy, Adjuvant
  • Radiotherapy, Conformal
  • Rectal Neoplasms/drug therapy/pathology/radiotherapy
  • Survival Analysis
  • Time Factors
  • Treatment Outcome
Citation (ISO format)
ALLAL, Abdelkarim Said et al. Preoperative concomitant hyperfractionated radiotherapy and gemcitabine for locally advanced rectal cancers: a phase I-II trial. In: The cancer journal, 2005, vol. 11, n° 2, p. 133–139. doi: 10.1097/00130404-200503000-00008
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal1528-9117
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Update time03/14/2023 9:29:35 PM
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