Pre-retrieval reperfusion decreases cancer recurrence after rat ischemic liver graft transplantation

Oldani, Graziano; Crowe, Lindsey A; Orci, Lorenzo; Slits, Florence; Rubbia-Brandt, Laura; De Vito, Claudio; Morel, Philippe; Mentha, Gilles; Berney, Thierry; Vallée, Jean-Paul; Lacotte, Stéphanie; Toso, Christian

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Title		Pre-retrieval reperfusion decreases cancer recurrence after rat ischemic liver graft transplantation
Authors		Oldani, Graziano Crowe, Lindsey A Orci, Lorenzo Slits, Florence Rubbia-Brandt, Laura De Vito, Claudio Morel, Philippe Mentha, Gilles Berney, Thierry Vallée, Jean-Paul Lacotte, Stéphanie Toso, Christian show all authors [1 - 12]
Published in		Journal of Hepatology. 2014, vol. 61, no. 2, p. 278-85
Abstract		Liver transplantation from marginal donors is associated with ischemia/reperfusion (I/R) lesions, which may increase the risk of post-transplant hepatocellular carcinoma (HCC) recurrence. Graft reperfusion prior to retrieval (as for extracorporeal membrane oxygenation - ECMO) can prevent I/R lesions. The impact of I/R on the risk of cancer recurrence was assessed on a syngeneic Fischer-rat liver transplantation model.
Identifiers		DOI: 10.1016/j.jhep.2014.03.036 PMID: 24713189
Full text		Article (Published version) (2.4 MB) - Free access
Structures		Faculté de médecine / Section de médecine clinique / Département de chirurgie Faculté de médecine / Section de médecine fondamentale / Département de pathologie et immunologie Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale
Research groups		Chirurgie viscérale (104) Métastases du foie (657) Hépatologie chirurgicale (327) La transplantation d'îlots de Langerhans (623) Imagerie cardiaque fonctionnelle (541) Transplantation et hépatologie (905)
Citation (ISO format)		OLDANI, Graziano et al. Pre-retrieval reperfusion decreases cancer recurrence after rat ischemic liver graft transplantation. In: Journal of Hepatology, 2014, vol. 61, n° 2, p. 278-85. https://archive-ouverte.unige.ch/unige:39093