Unsaturated fatty acids promote hepatoma proliferation and progression through downregulation of the tumor suppressor PTEN
Published inJournal of hepatology, vol. 50, no. 6, p. 1132-1141
Publication date2009
Abstract
Keywords
- Animals
- Apoptosis/drug effects
- Base Sequence
- Carcinogens/toxicity
- Cell Line, Tumor
- Cell Proliferation/drug effects
- Cell Survival/drug effects
- DNA Primers/genetics
- Down-Regulation/drug effects
- Fatty Acids, Unsaturated/toxicity
- Hepatocytes/drug effects/metabolism/pathology
- Humans
- Liver Neoplasms, Experimental/etiology/genetics/pathology
- Mice
- Mice, Nude
- Neoplasm Transplantation
- PTEN Phosphohydrolase/antagonists & inhibitors/genetics/metabolism
- RNA, Small Interfering/genetics
- Recombinant Fusion Proteins/genetics/metabolism
- Risk Factors
- Transfection
- Transplantation, Heterologous
Research group
Citation (ISO format)
VINCIGUERRA, Manlio et al. Unsaturated fatty acids promote hepatoma proliferation and progression through downregulation of the tumor suppressor PTEN. In: Journal of hepatology, 2009, vol. 50, n° 6, p. 1132–1141. doi: 10.1016/j.jhep.2009.01.027
Main files (1)
Article (Accepted version)
Identifiers
- PID : unige:3874
- DOI : 10.1016/j.jhep.2009.01.027
- PMID : 19398230
ISSN of the journal0168-8278