Lectin-deficient TNF mutants display comparable anti-tumour but reduced pro-metastatic potential as compared to the wild-type molecule
Publié dansInternational journal of cancer, vol. 91, no. 4, p. 543-549
Date de publication2001
Résumé
Mots-clés
- Animals
- Carcinoma, Lewis Lung
- Cattle
- Cell Adhesion
- Collagen/metabolism
- Dose-Response Relationship, Drug
- Endothelium, Vascular/cytology/metabolism
- Female
- Fibrosarcoma/genetics/metabolism
- Lectins/metabolism
- Lung/metabolism
- Melanoma, Experimental/genetics/metabolism
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Mutation
- Necrosis
- Neoplasm Metastasis
- Neoplasm Transplantation
- Neoplasms, Experimental
- Neovascularization, Pathologic
- Protein Structure, Tertiary
- Recombinant Proteins/metabolism
- Time Factors
- Tumor Cells, Cultured
- Tumor Necrosis Factor-alpha/chemistry/genetics/therapeutic use
Citation (format ISO)
LUCAS, Rudolf et al. Lectin-deficient TNF mutants display comparable anti-tumour but reduced pro-metastatic potential as compared to the wild-type molecule. In: International journal of cancer, 2001, vol. 91, n° 4, p. 543–549. doi: 10.1002/1097-0215(200002)9999:9999<::aid-ijc1090>3.0.co;2-y
Fichiers principaux (1)
Article (Accepted version)
Identifiants
- PID : unige:3857
- DOI : 10.1002/1097-0215(200002)9999:9999<::aid-ijc1090>3.0.co;2-y
- PMID : 11251979
ISSN du journal0020-7136