IntAct: an open source molecular interaction database

Hermjakob, Henning; Montecchi-Palazzi, Luisa; Lewington, Chris; Mudali, Sugath; Kerrien, Samuel; Orchard, Sandra; Vingron, Martin; Roechert, Bernd; Roepstorff, Peter; Valencia, Alfonso; Margalit, Hanah; Armstrong, John; Bairoch, Amos Marc; Cesareni, Gianni; Sherman, David; Apweiler, Rolf

doi:10.1093/nar/gkh052

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Title		IntAct: an open source molecular interaction database
Authors		Hermjakob, Henning Montecchi-Palazzi, Luisa Lewington, Chris Mudali, Sugath Kerrien, Samuel Orchard, Sandra Vingron, Martin Roechert, Bernd Roepstorff, Peter Valencia, Alfonso Margalit, Hanah Armstrong, John Bairoch, Amos Marc Cesareni, Gianni Sherman, David Apweiler, Rolf show all authors [1 - 16]
Published in		Nucleic acids research. 2004, vol. 32, no. Database issue, p. D452-5
Abstract		IntAct provides an open source database and toolkit for the storage, presentation and analysis of protein interactions. The web interface provides both textual and graphical representations of protein interactions, and allows exploring interaction networks in the context of the GO annotations of the interacting proteins. A web service allows direct computational access to retrieve interaction networks in XML format. IntAct currently contains approximately 2200 binary and complex interactions imported from the literature and curated in collaboration with the Swiss-Prot team, making intensive use of controlled vocabularies to ensure data consistency. All IntAct software, data and controlled vocabularies are available at http://www.ebi.ac.uk/intact.
Keywords		Animals — Computational Biology — Databases, Protein — Humans — Information Storage and Retrieval — Internet — Protein Binding — Proteins/metabolism — Software — User-Computer Interface — Vocabulary, Controlled
Identifiers		DOI: 10.1093/nar/gkh052 PMID: 14681455
Full text		Article (Published version) (239 Kb) - Free access Other version: http://nar.oxfordjournals.org/content/32/suppl_1/D452.long
Structures		Faculté de médecine / Section de médecine fondamentale / Département de biologie structurale et bioinformatique
Research groups		Swiss Institute of Bioinformatics Swiss-Prot Research Group Calipho (80)
Citation (ISO format)		HERMJAKOB, Henning et al. IntAct: an open source molecular interaction database. In: Nucleic Acids Research, 2004, vol. 32, n° Database issue, p. D452-5. doi: 10.1093/nar/gkh052 https://archive-ouverte.unige.ch/unige:38344