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Title

Factors affecting subject-specific finite element models of implant-fitted rat bone specimens: critical analysis of a technical protocol
Authors
Piccinini, Marco
Cugnoni, Joël
Botsis, John
Zacchetti, Giovanna
Ammann, Patrick
Wiskott, Anselm
Published in Computer Methods in Biomechanics and Biomedical Engineering. 2014, vol. 17, no. 13, p. 1403-1417
Abstract The authors propose a protocol to derive finite element (FE) models from micro computer tomography scans of implanted rat bone. A semi-automatic procedure allows segmenting the images using specimen-specific bone mineral density (BMD) thresholds. An open-source FE model generator processes the segmented images to a quality tetrahedral mesh. The material properties assigned to each element are integrated from the BMD field. Piecewise, threshold-dependent density-elasticity relationships are implemented to limit the effects of metal artefacts. A detailed sensitivity study highlights the coherence of the generated models and quantifies the influence of the modelling parameters on the results. Two applications of the protocol are proposed. The stiffness of bare and implanted rat tibiae specimens is predicted by simulating three-point bending and inter-implant displacement, respectively. Results are compared with experimental tests. The mean value and the variability between the specimens are well captured in both tests.
Identifiers
PMID: 23724864
Full text
Article (Published version) (575 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Faculté de médecine / Section de médecine clinique / Département de médecine
Faculté de médecine / Section de médecine clinique / Département de réadaptation et gériatrie
Faculté de médecine / Section de médecine dentaire / Département de réhabilitation oro-faciale / Division de prothèse fixe et biomatériaux
Research group Etudes précliniques de l'ostéoporose (606)
Citation
(ISO format) 		PICCININI, Marco et al. Factors affecting subject-specific finite element models of implant-fitted rat bone specimens: critical analysis of a technical protocol. In: Computer Methods in Biomechanics and Biomedical Engineering, 2014, vol. 17, n° 13, p. 1403-1417. doi: 10.1080/10255842.2012.736502 https://archive-ouverte.unige.ch/unige:38112

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Deposited on : 2014-06-25

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