Scientific article
English

SCA15 due to large ITPR1 deletions in a cohort of 333 white families with dominant ataxia

Published inArchives of neurology, vol. 68, no. 5, p. 637-643
Publication date2011
Abstract

Deletions in ITPR1, coding for the inositol-triphosphate receptor type 1, have been recently identified in spinocerebellar ataxia type 15 (SCA15).

Keywords
  • Adolescent
  • Adult
  • Age of Onset
  • Aged
  • Atrophy
  • Cerebellum/pathology
  • Child
  • Child, Preschool
  • Disease Progression
  • European Continental Ancestry Group/genetics
  • Female
  • Gene Deletion
  • Genetic Predisposition to Disease
  • Humans
  • Inositol 1,4,5-Trisphosphate Receptors/genetics
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Nystagmus, Pathologic/genetics
  • Pedigree
  • Saccades/genetics
  • Sequence Analysis, DNA
  • Spinocerebellar Ataxias/genetics/pathology
Citation (ISO format)
MARELLI, Cecilia et al. SCA15 due to large ITPR1 deletions in a cohort of 333 white families with dominant ataxia. In: Archives of neurology, 2011, vol. 68, n° 5, p. 637–643. doi: 10.1001/archneurol.2011.81
Main files (1)
Article (Accepted version)
accessLevelRestricted
Identifiers
Journal ISSN0003-9942
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Technical informations

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