Privat-docent thesis

The complexity of weaning critically ill patients from the ventilator

ContributorsPerren, Andréas
Defense date2012

Mechanical ventilation is often life-saving but at the same time it is also hazardous. Definitive liberation from the ventilator should be realized at the earliest possible moment in a patient's clinical course, as both premature and delayed extubation may negatively affect morbidity and mortality. There is now substantial proof, that a two-step diagnostic approach is the most performing way to achieve smooth and successful weaning for these patients. The first step consists in careful evaluation of the suspected ready-to-wean patient (assessment of weaning readiness). Ascertained readiness to wean is confirmed by the second step, a stress test. A patient's tolerance to this trial usually leads to definite removal of the endotracheal tube, whereas contrarily - weaning failure - a structured and thorough diagnostic work-up regarding potentially reversible pathologies has to be carried out.

  • Mechanical ventilation
  • Weaning
  • Prolonged ventilation
Citation (ISO format)
PERREN, Andréas. The complexity of weaning critically ill patients from the ventilator. 2012. doi: 10.13097/archive-ouverte/unige:37799
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Technical informations

Creation05/19/2014 3:34:00 PM
First validation05/19/2014 3:34:00 PM
Update time03/14/2023 9:20:57 PM
Status update03/14/2023 9:20:57 PM
Last indexation01/29/2024 8:10:04 PM
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