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Title

Oxaliplatin combined with irinotecan and 5-fluorouracil/leucovorin (OCFL) in metastatic colorectal cancer: a phase I-II study

Authors
Stupp, R
Ruhstaller, T
Philippe, M
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Published in Annals of Oncology. 2005, vol. 16, no. 5, p. 762-6
Abstract A phase I-II multicenter trial was conducted to define the maximal tolerated dose and describe the activity of an OCFL combination using oxaliplatin (OHP), irinotecan (CPT-11) and 5-fluorouracil (FU)/leucovorin (LV) in metastatic colorectal cancer (CRC).
Keywords AdultAgedAntineoplastic Combined Chemotherapy Protocols/adverse effects/therapeutic useCamptothecin/adverse effects/analogs & derivatives/therapeutic useColorectal Neoplasms/drug therapy/mortality/pathologyDose-Response Relationship, DrugDrug Administration ScheduleFemaleFluorouracil/adverse effects/therapeutic useHumansLeucovorin/adverse effects/therapeutic useLiver Neoplasms/drug therapy/secondaryLung Neoplasms/drug therapy/secondaryMaleMaximum Tolerated DoseMiddle AgedNeoplasm MetastasisNeoplasm StagingOrganoplatinum Compounds/adverse effects/therapeutic usePalliative CarePrognosisSurvival AnalysisTreatment Outcome
Identifiers
PMID: 15817597
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Article (Published version) (70 Kb) - public document Free access
Structures
Research groups Groupe Roth Arnaud (oncologie) (285)
Hépatologie chirurgicale (327)
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(ISO format)
SEIUM NEBERAY, Yodit et al. Oxaliplatin combined with irinotecan and 5-fluorouracil/leucovorin (OCFL) in metastatic colorectal cancer: a phase I-II study. In: Annals of Oncology, 2005, vol. 16, n° 5, p. 762-6. https://archive-ouverte.unige.ch/unige:37066

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Deposited on : 2014-06-03

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