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Progressive tissue injury in burns is reduced by rNAPc2

Tenorio, Xavier
Published in Burns. 2006, vol. 32, no. 8, p. 957-63
Abstract Burn wounds are characterised by central necrosis surrounded by an area of stasis with compromised perfusion. Secondary aggravation of the burn wound due to ischaemia in the zone of stasis can also result in necrosis. This study aims to improve circulation in the zone of stasis by reducing microthrombus formation and thereby to reduce secondary aggravation.
Keywords AnimalsAnticoagulants/therapeutic useBurns/drug therapy/pathologyCicatrixContracture/prevention & controlFibrin/analysisFlow CytometryHelminth Proteins/therapeutic useMaleRandom AllocationRatsRats, WistarRecombinant Proteins/therapeutic useRegional Blood Flow/drug effects
PMID: 16905262
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Research group Groupe Pittet Cuenod Brigitte (chirurgie plastique et reconstructive) (96)
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MAHAJAN, Ajay Liladhar et al. Progressive tissue injury in burns is reduced by rNAPc2. In: Burns, 2006, vol. 32, n° 8, p. 957-63. doi: 10.1016/j.burns.2006.02.010 https://archive-ouverte.unige.ch/unige:37009

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Deposited on : 2014-05-30

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