Conventional and scanning near-field optical microscopy techniques are cross referenced to femtosecond nonlinear-optical measurements and finite-element numerical simulations to visualize and analyze a strong confinement of electromagnetic radiation in guided modes of a photonic-crystal fiber with only a few air holes surrounding the fiber core. A nonlinear coefficient of about 120 W−1 km−1 is achieved at the wavelength of 670 nm for a fused-silica fiber with a full hexagonal cycle of closely packed air holes around the fiber core. The removal of a single element from this array of air holes is shown to frustrate field confinement in guided modes, leading to mode leakage