Cell adhesion and migration are critical for the development of multicellular organisms and the maintenance of tissue integrity. This thesis explores the roles of the growth factor "Stem Cell factor and its receptor c-kit, in the process of cell migration and developmental patterning. In addition changes of the cytoskeleton and adhesion receptors of the family of integrins were analysed by live cell imaging and quantitative dynamic analysis. The thesis focusses on the specific contributions of the author to this field of cell adhesion, migration and morphogenesis.