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Titles listEpigenetic control of tissue-type plasminogen activator synthesis in human endothelial cells
Titles listEpigenetic control of tissue-type plasminogen activator synthesis in human endothelial cells
Scientific Article
unige:36185 
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Epigenetic control of tissue-type plasminogen activator synthesis in human endothelial cells |
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| Authors | ||
| Published in | Cardiovascular Research. 2011, vol. 90, no. 3, p. 457-63 | |
| Abstract | Tissue-type plasminogen activator (t-PA) is produced by endothelial cells (EC) and is responsible for the removal of intravascular fibrin deposits. We investigated whether expression of t-PA by EC is under epigenetic control. | |
| Keywords | Base Sequence — Cells, Cultured — DNA Methylation — DNA Primers/genetics — Endothelial Cells/drug effects/metabolism — Epigenesis, Genetic/drug effects — Hepatocytes/metabolism — Histone Deacetylase Inhibitors/pharmacology — Histone Deacetylases/metabolism — Histones/metabolism — Humans — Promoter Regions, Genetic — RNA, Messenger/genetics/metabolism — Tissue Plasminogen Activator/biosynthesis/genetics | |
| Identifiers | DOI: 10.1093/cvr/cvr028 PMID: 21282301 | |
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| Structures | ||
| Research group | Endothélium vasculaire (11) | |
| Citation (ISO format) | GEINDRE, Sylvie Françoise, KRUITHOF, Egbert. Epigenetic control of tissue-type plasminogen activator synthesis in human endothelial cells. In: Cardiovascular Research, 2011, vol. 90, n° 3, p. 457-63. https://archive-ouverte.unige.ch/unige:36185 |
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