UNIGE document Scientific Article
previous document  unige:36185  next document
add to browser collection
Title

Epigenetic control of tissue-type plasminogen activator synthesis in human endothelial cells

Authors
Published in Cardiovascular Research. 2011, vol. 90, no. 3, p. 457-63
Abstract Tissue-type plasminogen activator (t-PA) is produced by endothelial cells (EC) and is responsible for the removal of intravascular fibrin deposits. We investigated whether expression of t-PA by EC is under epigenetic control.
Keywords Base SequenceCells, CulturedDNA MethylationDNA Primers/geneticsEndothelial Cells/drug effects/metabolismEpigenesis, Genetic/drug effectsHepatocytes/metabolismHistone Deacetylase Inhibitors/pharmacologyHistone Deacetylases/metabolismHistones/metabolismHumansPromoter Regions, GeneticRNA, Messenger/genetics/metabolismTissue Plasminogen Activator/biosynthesis/genetics
Identifiers
PMID: 21282301
Full text
Article (Published version) (285 Kb) - public document Free access
Structures
Research group Endothélium vasculaire (11)
Citation
(ISO format)
GEINDRE, Sylvie Françoise, KRUITHOF, Egbert. Epigenetic control of tissue-type plasminogen activator synthesis in human endothelial cells. In: Cardiovascular Research, 2011, vol. 90, n° 3, p. 457-63. https://archive-ouverte.unige.ch/unige:36185

186 hits

53 downloads

Update

Deposited on : 2014-04-29

Export document
Format :
Citation style :