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Scientific article
French

Procalcitonine: doser ou ne pas doser ?

Contributors

Luong Ba, Kim; Harbarth, Stéphan Juergen; Carballo, Sebastian

Published in

Revue médicale suisse, vol. 9, no. 402, p. 1881-1882,1884-5

Publication date

2013

Abstract

Procalcitonin (PCT) is a biomarker that is increasingly being used to help in decision making when managing febrile patients. This is a non exhaustive review of the literature regarding the use of PCT in deciding to begin or discontinue antibiotic treatment. PCT appears to be useful in patients with respiratory infections or sepsis. In both these situations and using evaluated algorithms, a low PCT (< 0.25 microg), enables withholding or discontinuing antibiotic treatment, without negatively affecting clinical outcomes. For other indications there is however insufficient evidence to support the systematic measurement of PCT in all febrile patients. In particular, in patients with autoimmune disease or in the postoperative setting, PCT is insufficiently sensitive or specific to rule out or confirm a bacterial infection requiring antibiotic treatment.

Keywords

  • Algorithms
  • Anti-Bacterial Agents/administration & dosage/therapeutic use
  • Bacterial Infections/diagnosis/drug therapy
  • Biological Markers/analysis
  • Calcitonin/analysis
  • Decision Making
  • Fever/diagnosis/drug therapy
  • Humans
  • Protein Precursors/analysis
  • Respiratory Tract Infections/diagnosis/drug therapy
  • Sensitivity and Specificity
  • Sepsis/diagnosis/drug therapy

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

LUONG BA, Kim, HARBARTH, Stéphan Juergen, CARBALLO, Sebastian. Procalcitonine: doser ou ne pas doser ? In: Revue médicale suisse, 2013, vol. 9, n° 402, p. 1881–1882,1884–5.

Main files (1)

Article (Published version)

Identifiers

Additional URL for this publication

http://rms.medhyg.ch/numero-402-page-1881.htm

Journal ISSN

1660-9379
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Technical informations

Creation

17/04/2014 09:07:00

First validation

17/04/2014 09:07:00

Update

13/10/2025 22:50:38

Status update

08/10/2024 09:18:45

Last indexation

10/11/2026 13:15:03
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