UNIGE document Scientific Article
previous document  unige:35887  next document
add to browser collection
Title

Dual-Task Assessment in Natalizumab-Treated Multiple Sclerosis Patients

Authors
Published in European Neurology. 2014, vol. 71, no. 5-6, p. 247-251
Abstract Background: To study the 1-year evolution of quantitative dual-task gait parameters in comparison with single-task gait parameters and detailed neuropsychological assessment in patients with multiple sclerosis (MS) treated with natalizumab. Methods: Walking speed, stride length and stride time during a dual task (walking while forward counting, backward counting, semantic fluency, and phonemic fluency), a single walking task, and a detailed neuropsychological assessment were prospectively measured and assessed twice at the 1-year interval in 9 consecutive patients with MS treated with natalizumab. Results: Dual-task-related gait changes (walking speed, stride length and stride time while performing semantic fluency and walking speed, and stride time while performing phonemic fluency) showed a significant improvement after 1 year of treatment with natalizumab. The single walking task and detailed neuropsychological assessment did not present any modification. Conclusions: Dual-task-related gait changes using a cognitive task with a specific executive demand represent an interesting marker of disease-modifying therapy in patients with MS. © 2014 S. Karger AG, Basel.
Identifiers
PMID: 24503719
Full text
Article (Published version) (179 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Research groups Laboratoire de cinésiologie (943)
Scléroses en plaques, neuroimmunologie, encéphalite autoimmune expérimentale (843)
Neuropsychologie et neurologie comportementale (951)
Citation
(ISO format)
ALLALI, Gilles et al. Dual-Task Assessment in Natalizumab-Treated Multiple Sclerosis Patients. In: European Neurology, 2014, vol. 71, n° 5-6, p. 247-251. https://archive-ouverte.unige.ch/unige:35887

282 hits

4 downloads

Update

Deposited on : 2014-04-22

Export document
Format :
Citation style :