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Assessment of adult formulas for glomerular filtration rate estimation in children

ContributorsChehade, Hassib; Girardin, Eric; Iglesias, Katia; Ramseyer, Pascal; Frey, Peter; Bardy, Daniel; Mosig, Dolores; Cachat, Francois
Published inPediatric nephrology, vol. 28, no. 1, p. 105-114
Publication date2013
Abstract

Estimated glomerular filtration rate (eGFR) is an important diagnostic instrument in clinical practice. The National Kidney Foundation-Kidney Disease Quality Initiative (NKF-KDOQI) guidelines do not recommend using formulas developed for adults to estimate GFR in children; however, studies confirming these recommendations are scarce. The aim of our study was to evaluate the accuracy of the new Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula, the Modification of Diet in Renal Disease (MDRD) formula, and the Cockcroft-Gault formula in children with various stages of chronic kidney disease (CKD).

Keywords
  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Female
  • Glomerular Filtration Rate/physiology
  • Humans
  • Male
  • Nephrology/standards
  • Renal Insufficiency, Chronic/diagnosis
Affiliation
Research group
Citation (ISO format)
CHEHADE, Hassib et al. Assessment of adult formulas for glomerular filtration rate estimation in children. In: Pediatric nephrology, 2013, vol. 28, n° 1, p. 105–114. doi: 10.1007/s00467-012-2298-2
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Article (Published version)
accessLevelRestricted
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ISSN of the journal0931-041X
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