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Assessment of adult formulas for glomerular filtration rate estimation in children

Chehade, Hassib
Iglesias, Katia
Ramseyer, Pascal
Frey, Peter
Bardy, Daniel
Mosig, Dolores
Cachat, Francois
Published in Pediatric Nephrology. 2013, vol. 28, no. 1, p. 105-14
Abstract Estimated glomerular filtration rate (eGFR) is an important diagnostic instrument in clinical practice. The National Kidney Foundation-Kidney Disease Quality Initiative (NKF-KDOQI) guidelines do not recommend using formulas developed for adults to estimate GFR in children; however, studies confirming these recommendations are scarce. The aim of our study was to evaluate the accuracy of the new Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula, the Modification of Diet in Renal Disease (MDRD) formula, and the Cockcroft-Gault formula in children with various stages of chronic kidney disease (CKD).
Keywords AdolescentAdultChildChild, PreschoolFemaleGlomerular Filtration Rate/physiologyHumansMaleNephrology/standardsRenal Insufficiency, Chronic/diagnosis
PMID: 22968331
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Research group Pathogénèse du syndrome néphrotique idiopathique de l'enfant (180)
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CHEHADE, Hassib et al. Assessment of adult formulas for glomerular filtration rate estimation in children. In: Pediatric Nephrology, 2013, vol. 28, n° 1, p. 105-14. doi: 10.1007/s00467-012-2298-2 https://archive-ouverte.unige.ch/unige:35510

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Deposited on : 2014-04-08

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