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Association of procalcitonin with acute pyelonephritis and renal scars in pediatric UTI.

Fernandez-Lopez, Anna
Nikfar, Roya
Romanello, Carla
Bouissou, François
Gurgoze, Metin K
Bressan, Silvia
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Published in Pediatrics. 2013, vol. 131, no. 5, p. 870-9
Abstract Urinary tract infections (UTIs) are common childhood bacterial infections that may involve renal parenchymal infection (acute pyelonephritis [APN]) followed by late scarring. Prompt, high-quality diagnosis of APN and later identification of children with scarring are important for preventing future complications. Examination via dimercaptosuccinic acid scanning is the current clinical gold standard but is not routinely performed. A more accessible assay could therefore prove useful. Our goal was to study procalcitonin as a predictor for both APN and scarring in children with UTI.
Keywords Acute DiseaseAdolescentArea Under CurveBiological Markers/bloodC-Reactive Protein/metabolismCalcitonin/blood/metabolismChildChild, PreschoolCicatrix/blood/epidemiology/prevention & controlConfidence IntervalsDisease ProgressionFemaleFollow-Up StudiesHumansIncidenceLikelihood FunctionsMaleOdds RatioPredictive Value of TestsProtein Precursors/blood/metabolismPyelonephritis/blood/diagnosis/epidemiologyRisk AssessmentSeverity of Illness IndexUrinary Tract Infections/diagnosis/drug therapy/epidemiology
PMID: 23629615
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Research group Etiologie des pneumonies et marqueurs inflammatoires chez l'enfant fébrile (183)
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LEROY, Sandrine et al. Association of procalcitonin with acute pyelonephritis and renal scars in pediatric UTI. In: Pediatrics, 2013, vol. 131, n° 5, p. 870-9. doi: 10.1542/peds.2012-2408 https://archive-ouverte.unige.ch/unige:35258

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Deposited on : 2014-04-02

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