Do children with uncomplicated severe acute malnutrition need antibiotics? A systematic review and meta-analysis

Alcoba Wright, Fermin Gabriel; Kerac, Marko; Breysse, Serge; Salpeteur, Cécile; Galetto-Lacour, Annick; Briend, André; Gervaix, Alain

doi:10.1371/journal.pone.0053184

Scientific article

Review

Open access

English

Do children with uncomplicated severe acute malnutrition need antibiotics? A systematic review and meta-analysis

ContributorsAlcoba Wright, Fermin Gabriel; Kerac, Marko; Breysse, Serge; Salpeteur, Cécile; Galetto-Lacour, Annick; Briend, André; Gervaix, Alain

Published inPloS one, vol. 8, no. 1, e53184

Publication date2013

Abstract

Current (1999) World Health Organization guidelines recommend giving routine antibiotics (AB) for all children with severe acute malnutrition (SAM), even if they have uncomplicated disease with no clinically obvious infections. We examined the evidence behind this recommendation.

Keywords

Acute Disease
Amoxicillin/therapeutic use
Anti-Bacterial Agents/therapeutic use
Bacteria/drug effects
Bacterial Infections/complications/drug therapy/microbiology
Ceftriaxone/therapeutic use
Child
Child Nutrition Disorders/complications/drug therapy/pathology
Child, Preschool
Humans
Practice Guidelines as Topic

Affiliation

Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique

Research group

Etiologie des pneumonies et marqueurs inflammatoires chez l'enfant fébrile (183)

Citation (ISO format)

ALCOBA WRIGHT, Fermin Gabriel et al. Do children with uncomplicated severe acute malnutrition need antibiotics? A systematic review and meta-analysis. In: PloS one, 2013, vol. 8, n° 1, p. e53184. doi: 10.1371/journal.pone.0053184

Article (Published version)

CC BY

Identifiers

PID : unige:35195
DOI : 10.1371/journal.pone.0053184
PMID : 23326395

ISSN of the journal1932-6203

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Do children with uncomplicated severe acute malnutrition need antibiotics? A systematic review and meta-analysis

Current (1999) World Health Organization guidelines recommend giving routine antibiotics (AB) for all children with severe acute malnutrition (SAM), even if they have uncomplicated disease with no clinically obvious infections. We examined the evidence behind this recommendation.

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