Targeted temperature management at 33°C versus 36°C after cardiac arrest

Nielsen, Niklas; Wetterslev, Jørn; Cronberg, Tobias; Erlinge, David; Gasche, Yvan; Hassager, Christian; Horn, Janneke; Hovdenes, Jan; Kjaergaard, Jesper; Kuiper, Michael; Pellis, Tommaso; Stammet, Pascal; Wanscher, Michael; Wise, Matt P; Åneman, Anders; Al-Subaie, Nawaf; Boesgaard, Søren; Bro-Jeppesen, John; Brunetti, Iole; Bugge, Jan Frederik; Hingston, Christopher D; Juffermans, Nicole P; Koopmans, Matty; Køber, Lars; Langørgen, Jørund; Lilja, Gisela; Møller, Jacob Eifer; Rundgren, Malin; Rylander, Christian; Smid, Ondrej; Werer, Christophe; Winkel, Per; Friberg, Hans

doi:10.1056/NEJMoa1310519

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Title		Targeted temperature management at 33°C versus 36°C after cardiac arrest
Authors		Nielsen, Niklas Wetterslev, Jørn Cronberg, Tobias Erlinge, David Gasche, Yvan Hassager, Christian Horn, Janneke Hovdenes, Jan Kjaergaard, Jesper Kuiper, Michael Pellis, Tommaso Stammet, Pascal Wanscher, Michael Wise, Matt P Åneman, Anders Al-Subaie, Nawaf Boesgaard, Søren Bro-Jeppesen, John Brunetti, Iole Bugge, Jan Frederik Hingston, Christopher D Juffermans, Nicole P Koopmans, Matty Køber, Lars Langørgen, Jørund Lilja, Gisela Møller, Jacob Eifer Rundgren, Malin Rylander, Christian Smid, Ondrej Werer, Christophe Winkel, Per Friberg, Hans show all authors [1 - 33]
Published in		The New England journal of medicine. 2013, vol. 369, no. 23, p. 2197-206
Abstract		Unconscious survivors of out-of-hospital cardiac arrest have a high risk of death or poor neurologic function. Therapeutic hypothermia is recommended by international guidelines, but the supporting evidence is limited, and the target temperature associated with the best outcome is unknown. Our objective was to compare two target temperatures, both intended to prevent fever.
Keywords		Adult — Aged — Body Temperature — Cardiopulmonary Resuscitation/methods — Female — Follow-Up Studies — Humans — Hypothermia, Induced — Kaplan-Meier Estimate — Male — Middle Aged — Models, Statistical — Out-of-Hospital Cardiac Arrest/complications/mortality/therapy — Treatment Failure — Unconsciousness/etiology — Withholding Treatment
Identifiers		DOI: 10.1056/NEJMoa1310519 PMID: 24237006
Full text		Article (Published version) (547 Kb) - Free access
Structures		Faculté de médecine / Section de médecine clinique / Département d'anesthésiologie, pharmacologie, soins intensifs et urgences
Research group		Groupe Gasche Yvan (Soins intensifs) (501)
Citation (ISO format)		NIELSEN, Niklas et al. Targeted temperature management at 33°C versus 36°C after cardiac arrest. In: The New England journal of medicine, 2013, vol. 369, n° 23, p. 2197-206. doi: 10.1056/NEJMoa1310519 https://archive-ouverte.unige.ch/unige:35178