UNIGE document Scientific Article
previous document  unige:35175  next document
add to browser collection
Title

Detailed statistical analysis plan for the target temperature management after out-of-hospital cardiac arrest trial

Authors
Nielsen, Niklas
Winkel, Per
Cronberg, Tobias
Erlinge, David
Friberg, Hans
Hassager, Christian
Horn, Janneke
show hidden authors show all authors [1 - 17]
Published in Trials. 2013, vol. 14, 300
Abstract Animal experimental studies and previous randomized trials suggest an improvement in mortality and neurological function with temperature regulation to hypothermia after cardiac arrest. According to a systematic review, previous trials were small, had a risk of bias, evaluated select populations, and did not treat hyperthermia in the control groups. The optimal target temperature management (TTM) strategy is not known. To prevent outcome reporting bias, selective reporting and data-driven results, we present the a priori defined detailed statistical analysis plan as an update to the previously published outline of the design and rationale for the TTM trial.
Identifiers
PMID: 24044764
Full text
Article (Published version) (318 Kb) - public document Free access
Structures
Research group Groupe Gasche Yvan (Soins intensifs) (501)
Citation
(ISO format)
NIELSEN, Niklas et al. Detailed statistical analysis plan for the target temperature management after out-of-hospital cardiac arrest trial. In: Trials, 2013, vol. 14, p. 300. doi: 10.1186/1745-6215-14-300 https://archive-ouverte.unige.ch/unige:35175

461 hits

222 downloads

Update

Deposited on : 2014-04-01

Export document
Format :
Citation style :