Treatment strategies for the management of advanced colorectal liver metastases detected synchronously with the primary tumour

Mentha, Gilles; Majno, Pietro; Terraz, Sylvain; Rubbia-Brandt, Laura; Gervaz, Pascal; Andres, Axel; Allal, Abdelkarim Said; Morel, Philippe; Roth, Arnaud

doi:10.1016/j.ejso.2007.09.016

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Title		Treatment strategies for the management of advanced colorectal liver metastases detected synchronously with the primary tumour
Authors		Mentha, Gilles Majno, Pietro Terraz, Sylvain Rubbia-Brandt, Laura Gervaz, Pascal Andres, Axel Allal, Abdelkarim Said Morel, Philippe Roth, Arnaud show all authors [1 - 9]
Published in		European journal of surgical oncology. 2007, vol. 33 Suppl 2, p. S76-83
Abstract		The review summarises the contributions of chemotherapy, interventional radiology and surgery to the improved survival observed in patients with colorectal liver metastases. The rationale in favour of modern neoadjuvant chemotherapy regimens, of pro-generative manoeuvres to increase the volume of the future remnant liver, and of resection techniques that preserve its function is discussed. For advanced synchronous colorectal metastases, the arguments in favour of a reversed approach with systemic chemotherapy, liver surgery and colon surgery in that order, as opposed to the traditional approach of colon surgery first, or to a simultaneous liver and large bowel resection, are presented.
Keywords		Antineoplastic Agents/therapeutic use — Catheter Ablation — Colectomy — Colorectal Neoplasms/pathology/therapy — Combined Modality Therapy — Embolization, Therapeutic — Hepatectomy — Humans — Liver Neoplasms/secondary/therapy — Neoplasms, Multiple Primary/therapy — Portal Vein
Identifiers		DOI: 10.1016/j.ejso.2007.09.016 PMID: 18006267
Full text		Article (Published version) (187 Kb) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de médecine Faculté de médecine / Section de médecine clinique / Département de chirurgie Faculté de médecine / Section de médecine fondamentale / Département de pathologie et immunologie Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale
Research groups		Chirurgie viscérale (104) Chirurgie viscérale (HUG) Groupe Roth Arnaud (oncologie) (285) Hépatologie chirurgicale (327) Métastases du foie (657)
Citation (ISO format)		MENTHA, Gilles et al. Treatment strategies for the management of advanced colorectal liver metastases detected synchronously with the primary tumour. In: European journal of surgical oncology, 2007, vol. 33 Suppl 2, p. S76-83. doi: 10.1016/j.ejso.2007.09.016 https://archive-ouverte.unige.ch/unige:35043