Blockade of the PD-1/PD-1L pathway reverses the protective effect of anti-CD40L therapy in a rat to mouse concordant islet xenotransplantation model
Published inXenotransplantation, vol. 14, no. 3, p. 243-248
Publication date2007
Abstract
Keywords
- Animals
- Antibodies, Monoclonal
- Antigens, CD274
- Antigens, CD80/immunology
- Antigens, Differentiation/immunology
- CD40 Ligand/antagonists & inhibitors/immunology
- Cricetinae
- Cricetulus/immunology
- Diabetes Mellitus/chemically induced
- Disease Models, Animal
- Graft Survival/immunology
- Islets of Langerhans Transplantation/immunology/methods
- Membrane Glycoproteins/antagonists & inhibitors/immunology
- Mice
- Mice, Inbred C57BL
- Peptides/antagonists & inhibitors/immunology
- Rats
- Rats, Sprague-Dawley
- Signal Transduction/drug effects/immunology
- Transplantation, Heterologous/immunology/methods
Affiliation
Research group
Citation (ISO format)
MAI, Gang et al. Blockade of the PD-1/PD-1L pathway reverses the protective effect of anti-CD40L therapy in a rat to mouse concordant islet xenotransplantation model. In: Xenotransplantation, 2007, vol. 14, n° 3, p. 243–248. doi: 10.1111/j.1399-3089.2007.00402.x
Main files (1)
Article (Published version)
Identifiers
- PID : unige:35014
- DOI : 10.1111/j.1399-3089.2007.00402.x
- PMID : 17489865
ISSN of the journal0908-665X