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Scientific article
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English

A new disposable perfusion machine, nuclear magnetic resonance compatible, to test the marginal organs and the kidneys from non-heart-beating donors before transplantation

Contributors

Buchs, Jean-Bernard; Buehler, Leo Hans; Morel, Philippe

Published in

Interactive cardiovascular and thoracic surgery, vol. 6, no. 4, p. 421-424

Publication date

2007

Abstract

This article is the first report about our new hypothermic pulsatile perfusion machine (HUG's HPP-machine) for kidney perfusion. This machine will be used for (31)P NMR spectroscopy. The aim is to obtain scores of viability of marginal kidneys and those from non-heart-beating donors (NHBD) before transplantation using HPP as it has been demonstrated necessary in these situations. The most predictable test is the ratio of phosphomonoester on inorganic phosphorus (PME/Pi) that can be obtained from (31)P spectroscopy. The machine has been built to allow perfusion of kidneys in the range of that performed with the traditional Belzer, Mox-Waters machines and others, but compatible with the magnetic fields of the MRI apparatus used for (31)P NMR spectroscopy. In this publication, the technical aspects of this new aerobic HPP-machine compatible with MRI is presented.

Keywords

  • Animals
  • Disposable Equipment
  • Kidney
  • Kidney Transplantation
  • Magnetic Resonance Spectroscopy/diagnostic use
  • Organ Preservation
  • Pulsatile Flow
  • Renal Circulation
  • Swine
  • Swine, Miniature
  • Tissue Donors
  • Tissue Survival

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

BUCHS, Jean-Bernard, BUEHLER, Leo Hans, MOREL, Philippe. A new disposable perfusion machine, nuclear magnetic resonance compatible, to test the marginal organs and the kidneys from non-heart-beating donors before transplantation. In: Interactive cardiovascular and thoracic surgery, 2007, vol. 6, n° 4, p. 421–424. doi: 10.1510/icvts.2006.146043

Main files (1)

Article (Published version)

Identifiers

Journal ISSN

1569-9285
751views
361downloads

Technical informations

Creation

28/02/2014 11:32:00

First validation

28/02/2014 11:32:00

Update

14/03/2023 21:00:53

Status update

14/03/2023 21:00:53

Last indexation

30/10/2024 16:27:34
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