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A new disposable perfusion machine, nuclear magnetic resonance compatible, to test the marginal organs and the kidneys from non-heart-beating donors before transplantation

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Published in Interactive Cardiovascular and Thoracic Surgery. 2007, vol. 6, no. 4, p. 421-4
Abstract This article is the first report about our new hypothermic pulsatile perfusion machine (HUG's HPP-machine) for kidney perfusion. This machine will be used for (31)P NMR spectroscopy. The aim is to obtain scores of viability of marginal kidneys and those from non-heart-beating donors (NHBD) before transplantation using HPP as it has been demonstrated necessary in these situations. The most predictable test is the ratio of phosphomonoester on inorganic phosphorus (PME/Pi) that can be obtained from (31)P spectroscopy. The machine has been built to allow perfusion of kidneys in the range of that performed with the traditional Belzer, Mox-Waters machines and others, but compatible with the magnetic fields of the MRI apparatus used for (31)P NMR spectroscopy. In this publication, the technical aspects of this new aerobic HPP-machine compatible with MRI is presented.
Keywords AnimalsDisposable EquipmentKidneyKidney TransplantationMagnetic Resonance Spectroscopy/diagnostic useOrgan PreservationPulsatile FlowRenal CirculationSwineSwine, MiniatureTissue DonorsTissue Survival
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PMID: 17669888
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Article (Published version) (1.6 MB) - public document Free access
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Research group Chirurgie viscérale (104)
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BUCHS, Jean-Bernard, BUEHLER, Leo Hans, MOREL, Philippe. A new disposable perfusion machine, nuclear magnetic resonance compatible, to test the marginal organs and the kidneys from non-heart-beating donors before transplantation. In: Interactive Cardiovascular and Thoracic Surgery, 2007, vol. 6, n° 4, p. 421-4. https://archive-ouverte.unige.ch/unige:34692

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Deposited on : 2014-03-10

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