UNIGE document Scientific Article
previous document  unige:34382  next document
add to browser collection
Title

Tumeurs stromales gastro-intestinales

Authors
Published in Revue médicale suisse. 2008, vol. 4, no. 163, p. 1567-70
Abstract Gastrointestinal stromal tumors (GIST) are the most common digestive mesenchymal tumors. GIST characterized by over-expression of the tyrosine kinase receptor KIT. GIST span a wide clinical spectrum from benign to highly malignant. Surgery is the only curative treatment for GIST. Low malignant GIST have an excellent prognosis after surgical treatment (5 years survival rate > 90%). Highly malignant GIST have an extremely poor prognosis even after surgical resection (median survival < 12 months). The development of tyrosine kinase inhibitors has changed the management of unresectable GIST. One of them, imatinib mesylate, has been proved to improve survival of metastatic GIST. This paper reviews literature data on GIST.
Keywords AlgorithmsGastrointestinal Stromal Tumors/diagnosis/surgeryHumans
Identifiers
PMID: 18672547
Full text
Article (Published version) (2.2 MB) - document accessible for UNIGE members only Limited access to UNIGE
Other version: http://rms.medhyg.ch/numero-163-page-1567.htm
Structures
Research group Chirurgie viscérale (104)
Citation
(ISO format)
BUCHER, Pascal Alain Robert, MOREL, Philippe. Tumeurs stromales gastro-intestinales. In: Revue médicale suisse, 2008, vol. 4, n° 163, p. 1567-70. https://archive-ouverte.unige.ch/unige:34382

107 hits

0 download

Update

Deposited on : 2014-02-19

Export document
Format :
Citation style :