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Title

Assessment of operability of patients with pulmonary arterial hypertension associated with congenital heart disease

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Published in Circulation Journal. 2013, vol. 78, no. 1, p. 4-11+ corrigendum
Abstract Pulmonary arterial hypertension (PAH) is a common complication of congenital heart disease, and is now predominantly among patients with uncorrected left-to-right shunts. A growing population is characterized by persistent or recurrent PAH after surgical or interventional correction of left-to-right shunts; the latter having a worse prognosis than other forms of PAH associated with congenital heart disease. New treatments for PAH have been shown to be effective in improving PAH exercise capacity and hemodynamics, raising the hope for making previously inoperable congenital heart defects operable and shifting the framework for the assessment of operability. This review focuses on current methods for assessing operability in PAH associated with congenital heart disease, and the possibility of "treat-and-repair" vs. "repair-and-treat" strategies for patients with inoperable or borderline PAH.
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PMID: 24225339
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Article (Published version) (660 Kb) - public document Free access
Article (Published version) (352 Kb) - public document Free access
Structures
Research groups Chirurgie cardio-vasculaire (105)
L'hypertension pulmonaire (pédiatrie) (228)
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(ISO format)
MYERS, Patrick Olivier, TISSOT-DAGUETTE, Cécile, BEGHETTI, Maurice. Assessment of operability of patients with pulmonary arterial hypertension associated with congenital heart disease. In: Circulation Journal, 2013, vol. 78, n° 1, p. 4-11+ corrigendum. https://archive-ouverte.unige.ch/unige:34325

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Deposited on : 2014-02-14

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